An Antimicrobial Peptidomimetic Induces Mucorales Cell Death through Mitochondria-Mediated Apoptosis

The incidence of mucormycosis has dramatically increased in immunocompromised patients. Moreover, the array of cellular targets whose inhibition results in fungal cell death is rather limited. Mitochondria have been mechanistically identified as central regulators of detoxification and virulence in...

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Detalles Bibliográficos
Autores principales: Barbu, E. Magda, Shirazi, Fazal, McGrath, Danielle M., Albert, Nathaniel, Sidman, Richard L., Pasqualini, Renata, Arap, Wadih, Kontoyiannis, Dimitrios P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789667/
https://www.ncbi.nlm.nih.gov/pubmed/24098573
http://dx.doi.org/10.1371/journal.pone.0076981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789667/
https://www.ncbi.nlm.nih.gov/pubmed/24098573
http://dx.doi.org/10.1371/journal.pone.0076981

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