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An Antimicrobial Peptidomimetic Induces Mucorales Cell Death through Mitochondria-Mediated Apoptosis
The incidence of mucormycosis has dramatically increased in immunocompromised patients. Moreover, the array of cellular targets whose inhibition results in fungal cell death is rather limited. Mitochondria have been mechanistically identified as central regulators of detoxification and virulence in...
Autores principales: | Barbu, E. Magda, Shirazi, Fazal, McGrath, Danielle M., Albert, Nathaniel, Sidman, Richard L., Pasqualini, Renata, Arap, Wadih, Kontoyiannis, Dimitrios P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789667/ https://www.ncbi.nlm.nih.gov/pubmed/24098573 http://dx.doi.org/10.1371/journal.pone.0076981 |
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