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Select Dietary Phytochemicals Function as Inhibitors of COX-1 but Not COX-2

Recent clinical trials raised concerns regarding the cardiovascular toxicity of selective cyclooxygenase-2 (COX-2) inhibitors. Many active dietary factors are reported to suppress carcinogenesis by targeting COX-2. A major question was accordingly raised: why has the lifelong use of phytochemicals t...

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Detalles Bibliográficos
Autores principales: Li, Haitao, Zhu, Feng, Sun, Yanwen, Li, Bing, Oi, Naomi, Chen, Hanyong, Lubet, Ronald A., Bode, Ann M., Dong, Zigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789677/
https://www.ncbi.nlm.nih.gov/pubmed/24098505
http://dx.doi.org/10.1371/journal.pone.0076452