Cargando…

Select Dietary Phytochemicals Function as Inhibitors of COX-1 but Not COX-2

Recent clinical trials raised concerns regarding the cardiovascular toxicity of selective cyclooxygenase-2 (COX-2) inhibitors. Many active dietary factors are reported to suppress carcinogenesis by targeting COX-2. A major question was accordingly raised: why has the lifelong use of phytochemicals t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Haitao, Zhu, Feng, Sun, Yanwen, Li, Bing, Oi, Naomi, Chen, Hanyong, Lubet, Ronald A., Bode, Ann M., Dong, Zigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789677/ https://www.ncbi.nlm.nih.gov/pubmed/24098505 http://dx.doi.org/10.1371/journal.pone.0076452

Ejemplares similares

Prediction of Molecular Targets of Cancer Preventing Flavonoid Compounds Using Computational Methods
por: Chen, Hanyong, et al.
Publicado: (2012)

UVB-induced COX-2 expression requires histone H3 phosphorylation at Ser10 and Ser28
por: Keum, Young-Sam, et al.
Publicado: (2012)

Selective COX-2 inhibitor versus non-selective COX-2 inhibitor for the prevention of heterotopic ossification after total hip arthroplasty: A meta-analysis
por: Zhu, Xi-Tian, et al.
Publicado: (2018)

Anaphylaxis to selective COX-2 inhibitors: an unexpected culprit
por: Dias de Castro, Eunice, et al.
Publicado: (2015)

Cox-2: where are we in 2003? - Cardiovascular risk and Cox-2 inhibitors
por: Mukherjee, Debabrata, et al.
Publicado: (2003)

COX inhibitors and breast cancer
por: Mazhar, D, et al.
Publicado: (2006)

Binding Energy Calculation of Patchouli Alcohol Isomer Cyclooxygenase Complexes Suggested as COX-1/COX-2 Selective Inhibitor
por: Raharjo, Sentot Joko, et al.
Publicado: (2014)

Design and Synthesis of Imidazopyrazolopyridines as Novel Selective COX-2 Inhibitors
por: Badrey, Mohamed G., et al.
Publicado: (2015)

COX-2 Inhibitors and Gastric Cancer
por: Wang, Zhen, et al.
Publicado: (2014)

Cyclooxygenase (COX) Inhibitors and the Newborn Kidney
por: Smith, Francine G., et al.
Publicado: (2012)

Thiazoles and Thiazolidinones as COX/LOX Inhibitors
por: Liaras, Konstantinos, et al.
Publicado: (2018)

Adverse Effects of COX-2 Inhibitors
por: Sharma, Jagdish N., et al.
Publicado: (2005)

Colorectal Carcinoma, Cyclooxygenases, and COX Inhibitors
por: Ganduri, Vinutna, et al.
Publicado: (2022)

Exploring the role of COX-2 in Alzheimer's disease: Potential therapeutic implications of COX-2 inhibitors
por: Moussa, Nathalie, et al.
Publicado: (2023)

COX-2: Where are we in 2003? - Be strong and resolute: continue to use COX-2 selective inhibitors at recommended dosages in appropriate patients
por: Hochberg, Marc C
Publicado: (2003)

Selective COX-2 inhibitor ameliorates osteoarthritis by repressing apoptosis of chondrocyte
por: Ou, Yunsheng, et al.
Publicado: (2012)

Selective COX-2 Inhibitors: A Review of Their Structure-Activity Relationships
por: Zarghi, Afshin, et al.
Publicado: (2011)

Molecular docking and analgesic studies of Erythrina variegata׳s derived phytochemicals with COX enzymes
por: Uddin, Mir Muhammad Nasir, et al.
Publicado: (2014)

Selective COX-2 inhibition affects fatty acids, but not COX mRNA expression in patients with FAP
por: Almendingen, Kari, et al.
Publicado: (2010)

Ensembling Variable Selectors by Stability Selection for the Cox Model
por: Yin, Qing-Yan, et al.
Publicado: (2017)

Flavonoids: Antiplatelet Effect as Inhibitors of COX-1
por: Zaragozá, Cristina, et al.
Publicado: (2022)

Houttuynia cordata, a novel and selective COX-2 inhibitor with anti-inflammatory activity
por: Li, Weifeng, et al.
Publicado: (2011)

Cyclooxygenase-1 (COX-1) and COX-1 Inhibitors in Cancer: A Review of Oncology and Medicinal Chemistry Literature
por: Pannunzio, Alessandra, et al.
Publicado: (2018)

Radiolabeled COX-2 Inhibitors for Non-Invasive Visualization of COX-2 Expression and Activity — A Critical Update
por: Laube, Markus, et al.
Publicado: (2013)

Selective COX-2 inhibitors, NSAIDs and cardiovascular events – is celecoxib the safest choice?
por: Howes, Laurence Guy
Publicado: (2007)

The 2′-Trifluoromethyl Analogue of Indomethacin Is a Potent and Selective COX-2 Inhibitor
por: Blobaum, Anna L., et al.
Publicado: (2013)

Reduction in cancer risk by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors
por: Harris, Randall E, et al.
Publicado: (2012)

Chondroprotective Actions of Selective COX-2 Inhibitors In Vivo: A Systematic Review
por: Timur, Ufuk Tan, et al.
Publicado: (2020)

Selective COX-2 Inhibitors: Road from Success to Controversy and the Quest for Repurposing
por: El-Malah, Afaf A., et al.
Publicado: (2022)

Phytochemical mediated modulation of COX-3 and NFκB for the management and treatment of arthritis
por: Biswas, Dipak, et al.
Publicado: (2023)

Sir James Coxe
Publicado: (1878)

Dr. Coxe, on Vaccination
por: Coxe, John Redman
Publicado: (1805)

Sir James Coxe
Publicado: (1878)

Dr. Joseph T. Cox
Publicado: (1918)

Bishop Coxe on Science
Publicado: (1869)

Upregulation of COX4-2 via HIF-1α in Mitochondrial COX4-1 Deficiency
por: Douiev, Liza, et al.
Publicado: (2021)

The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis
por: Lorenzi, Isotta, et al.
Publicado: (2018)

The nonsense-mediated mRNA decay (NMD) pathway differentially regulates COX17, COX19 and COX23 mRNAs
por: Murtha, Kaitlin, et al.
Publicado: (2018)

Seizure following the Use of the COX-2 Inhibitor Etoricoxib
por: Arnao, Valentina, et al.
Publicado: (2017)

Cox-2 inhibitors in mandibular third molar surgery
por: Janarthanan, K., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qasu5k9nnjp44jp8uvc55dr26c