How Changes in Extracellular Matrix Mechanics and Gene Expression Variability Might Combine to Drive Cancer Progression

Changes in extracellular matrix (ECM) structure or mechanics can actively drive cancer progression; however, the underlying mechanism remains unknown. Here we explore whether this process could be mediated by changes in cell shape that lead to increases in genetic noise, given that both factors have...

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Detalles Bibliográficos
Autores principales: Werfel, Justin, Krause, Silva, Bischof, Ashley G., Mannix, Robert J., Tobin, Heather, Bar-Yam, Yaneer, Bellin, Robert M., Ingber, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789713/
https://www.ncbi.nlm.nih.gov/pubmed/24098430
http://dx.doi.org/10.1371/journal.pone.0076122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789713/
https://www.ncbi.nlm.nih.gov/pubmed/24098430
http://dx.doi.org/10.1371/journal.pone.0076122

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