Cargando…

Purine Nucleoside Phosphorylase Targeted by Annexin V to Breast Cancer Vasculature for Enzyme Prodrug Therapy

BACKGROUND AND PURPOSE: The targeting of therapeutics is a promising approach for the development of new cancer treatments that seek to reduce the devastating side effects caused by the systemic administration of current drugs. This study evaluates a fusion protein developed as an enzyme prodrug the...

Descripción completa

Detalles Bibliográficos
Autores principales: Krais, John J., De Crescenzo, Olivier, Harrison, Roger G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789731/
https://www.ncbi.nlm.nih.gov/pubmed/24098491
http://dx.doi.org/10.1371/journal.pone.0076403