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Purine Nucleoside Phosphorylase Targeted by Annexin V to Breast Cancer Vasculature for Enzyme Prodrug Therapy
BACKGROUND AND PURPOSE: The targeting of therapeutics is a promising approach for the development of new cancer treatments that seek to reduce the devastating side effects caused by the systemic administration of current drugs. This study evaluates a fusion protein developed as an enzyme prodrug the...
Autores principales: | Krais, John J., De Crescenzo, Olivier, Harrison, Roger G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789731/ https://www.ncbi.nlm.nih.gov/pubmed/24098491 http://dx.doi.org/10.1371/journal.pone.0076403 |
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