Analysis of Nonlinear Gene Expression Progression Reveals Extensive Pathway and Age-Specific Transitions in Aging Human Brains

Several recent gene expression studies identified hundreds of genes that are correlated with age in brain and other tissues in human. However, these studies used linear models of age correlation, which are not well equipped to model abrupt changes associated with particular ages. We developed a comp...

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Detalles Bibliográficos
Autores principales: Cao, Kajia, Ryvkin, Paul, Hwang, Yih-Chii, Johnson, F. Brad, Wang, Li-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789733/
https://www.ncbi.nlm.nih.gov/pubmed/24098339
http://dx.doi.org/10.1371/journal.pone.0074578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789733/
https://www.ncbi.nlm.nih.gov/pubmed/24098339
http://dx.doi.org/10.1371/journal.pone.0074578

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