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Genome-Wide Association Study of Gene by Smoking Interactions in Coronary Artery Calcification

Many GWAS have identified novel loci associated with common diseases, but have focused only on main effects of individual genetic variants rather than interactions with environmental factors (GxE). Identification of GxE interactions is particularly important for coronary heart disease (CHD), a major...

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Detalles Bibliográficos
Autores principales: Polfus, Linda M., Smith, Jennifer A., Shimmin, Lawrence C., Bielak, Lawrence F., Morrison, Alanna C., Kardia, Sharon L. R., Peyser, Patricia A., Hixson, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789744/
https://www.ncbi.nlm.nih.gov/pubmed/24098343
http://dx.doi.org/10.1371/journal.pone.0074642