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Genome-Wide Association Study of Gene by Smoking Interactions in Coronary Artery Calcification
Many GWAS have identified novel loci associated with common diseases, but have focused only on main effects of individual genetic variants rather than interactions with environmental factors (GxE). Identification of GxE interactions is particularly important for coronary heart disease (CHD), a major...
Autores principales: | Polfus, Linda M., Smith, Jennifer A., Shimmin, Lawrence C., Bielak, Lawrence F., Morrison, Alanna C., Kardia, Sharon L. R., Peyser, Patricia A., Hixson, James E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789744/ https://www.ncbi.nlm.nih.gov/pubmed/24098343 http://dx.doi.org/10.1371/journal.pone.0074642 |
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