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Evaluation of Glutathione S-Transferase GSTM1 and GSTT1 Deletion Polymorphisms on Type-2 Diabetes Mellitus Risk

BACKGROUND: Due to the activity of GSTs in the detoxification of oxidative stress products, deletion polymorphisms of GSTM1 and GSTT1 may contribute to susceptibility to T2DM, since B-cells express very low levels of antioxidant enzymes. Recently, some studies have shown an association between GSTM1...

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Detalles Bibliográficos
Autores principales: Pinheiro, Denise S., Rocha Filho, César R., Mundim, Cláudia A., Júnior, Paulo de Marco, Ulhoa, Cirano J., Reis, Angela A. S., Ghedini, Paulo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789749/
https://www.ncbi.nlm.nih.gov/pubmed/24098457
http://dx.doi.org/10.1371/journal.pone.0076262