A Novel DNA Vaccine Technology Conveying Protection against a Lethal Herpes Simplex Viral Challenge in Mice

While there are a number of licensed veterinary DNA vaccines, to date, none have been licensed for use in humans. Here, we demonstrate that a novel technology designed to enhance the immunogenicity of DNA vaccines protects against lethal herpes simplex virus 2 (HSV-2) challenge in a murine model. Po...

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Detalles Bibliográficos
Autores principales: Dutton, Julie L., Li, Bo, Woo, Wai-Ping, Marshak, Joshua O., Xu, Yan, Huang, Meei-li, Dong, Lichun, Frazer, Ian H., Koelle, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789751/
https://www.ncbi.nlm.nih.gov/pubmed/24098493
http://dx.doi.org/10.1371/journal.pone.0076407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789751/
https://www.ncbi.nlm.nih.gov/pubmed/24098493
http://dx.doi.org/10.1371/journal.pone.0076407

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