TXNIP Deficiency Exacerbates Endotoxic Shock via the Induction of Excessive Nitric Oxide Synthesis

Thioredoxin-interacting protein (TXNIP) has multiple functions, including tumor suppression and involvement in cell proliferation and apoptosis. However, its role in the inflammatory process remains unclear. In this report, we demonstrate that Txnip(−/−) mice are significantly more susceptible to li...

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Detalles Bibliográficos
Autores principales: Park, Young-Jun, Yoon, Sung-Jin, Suh, Hyun-Woo, Kim, Dong Oh, Park, Jeong-Ran, Jung, Haiyoung, Kim, Tae-Don, Yoon, Suk Ran, Min, Jeong-Ki, Na, Hee-Jun, Lee, Seon-Jin, Lee, Hee Gu, Lee, Young Ho, Lee, Hee-Bong, Choi, Inpyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789754/
https://www.ncbi.nlm.nih.gov/pubmed/24098117
http://dx.doi.org/10.1371/journal.ppat.1003646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789754/
https://www.ncbi.nlm.nih.gov/pubmed/24098117
http://dx.doi.org/10.1371/journal.ppat.1003646

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