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A Mechanism for the Inhibition of DNA-PK-Mediated DNA Sensing by a Virus

The innate immune system is critical in the response to infection by pathogens and it is activated by pattern recognition receptors (PRRs) binding to pathogen associated molecular patterns (PAMPs). During viral infection, the direct recognition of the viral nucleic acids, such as the genomes of DNA...

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Detalles Bibliográficos
Autores principales: Peters, Nicholas E., Ferguson, Brian J., Mazzon, Michela, Fahy, Aodhnait S., Krysztofinska, Ewelina, Arribas-Bosacoma, Raquel, Pearl, Laurence H., Ren, Hongwei, Smith, Geoffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789764/
https://www.ncbi.nlm.nih.gov/pubmed/24098118
http://dx.doi.org/10.1371/journal.ppat.1003649