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A Mechanism for the Inhibition of DNA-PK-Mediated DNA Sensing by a Virus
The innate immune system is critical in the response to infection by pathogens and it is activated by pattern recognition receptors (PRRs) binding to pathogen associated molecular patterns (PAMPs). During viral infection, the direct recognition of the viral nucleic acids, such as the genomes of DNA...
Autores principales: | Peters, Nicholas E., Ferguson, Brian J., Mazzon, Michela, Fahy, Aodhnait S., Krysztofinska, Ewelina, Arribas-Bosacoma, Raquel, Pearl, Laurence H., Ren, Hongwei, Smith, Geoffrey L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789764/ https://www.ncbi.nlm.nih.gov/pubmed/24098118 http://dx.doi.org/10.1371/journal.ppat.1003649 |
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