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Targeted Deletion and Inversion of Tandemly Arrayed Genes in Arabidopsis thaliana Using Zinc Finger Nucleases

Tandemly arrayed genes (TAGs) or gene clusters are prevalent in higher eukaryotic genomes. For example, approximately 17% of genes are organized in tandem in the model plant Arabidopsis thaliana. The genetic redundancy created by TAGs presents a challenge for reverse genetics. As molecular scissors,...

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Detalles Bibliográficos
Autores principales: Qi, Yiping, Li, Xiaohong, Zhang, Yong, Starker, Colby G., Baltes, Nicholas J., Zhang, Feng, Sander, Jeffry D., Reyon, Deepak, Joung, J. Keith, Voytas, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789795/
https://www.ncbi.nlm.nih.gov/pubmed/23979943
http://dx.doi.org/10.1534/g3.113.006270