Cargando…

Targeted Deletion and Inversion of Tandemly Arrayed Genes in Arabidopsis thaliana Using Zinc Finger Nucleases

Tandemly arrayed genes (TAGs) or gene clusters are prevalent in higher eukaryotic genomes. For example, approximately 17% of genes are organized in tandem in the model plant Arabidopsis thaliana. The genetic redundancy created by TAGs presents a challenge for reverse genetics. As molecular scissors,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qi, Yiping, Li, Xiaohong, Zhang, Yong, Starker, Colby G., Baltes, Nicholas J., Zhang, Feng, Sander, Jeffry D., Reyon, Deepak, Joung, J. Keith, Voytas, Daniel F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2013
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789795/ https://www.ncbi.nlm.nih.gov/pubmed/23979943 http://dx.doi.org/10.1534/g3.113.006270

Ejemplares similares

ZFNGenome: A comprehensive resource for locating zinc finger nuclease target sites in model organisms
por: Reyon, Deepak, et al.
Publicado: (2011)

ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool
por: Sander, Jeffry D., et al.
Publicado: (2010)

Rapid Mutation of Endogenous Zebrafish Genes Using Zinc Finger Nucleases Made by Oligomerized Pool ENgineering (OPEN)
por: Foley, Jonathan E., et al.
Publicado: (2009)

Zinc Finger Database (ZiFDB): a repository for information on C2H2 zinc fingers and engineered zinc-finger arrays
por: Fu, Fengli, et al.
Publicado: (2009)

Selection-Free Zinc-Finger Nuclease Engineering by Context-Dependent Assembly (CoDA)
por: Sander, Jeffry D., et al.
Publicado: (2010)

Zinc Finger Targeter (ZiFiT): an engineered zinc finger/target site design tool
por: Sander, Jeffry D., et al.
Publicado: (2007)

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites
por: Sander, Jeffry D., et al.
Publicado: (2013)

Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion
por: Şöllü, Cem, et al.
Publicado: (2010)

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
por: Fu, Yanfang, et al.
Publicado: (2014)

Targeted Mutagenesis of Arabidopsis thaliana Using Engineered TAL Effector Nucleases
por: Christian, Michelle, et al.
Publicado: (2013)

High frequency modification of plant genes using engineered zinc finger nucleases
por: Townsend, Jeffrey A., et al.
Publicado: (2009)

Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
por: Sander, Jeffry D, et al.
Publicado: (2010)

An affinity-based scoring scheme for predicting DNA-binding activities of modularly assembled zinc-finger proteins
por: Sander, Jeffry D., et al.
Publicado: (2009)

Comparing Zinc Finger Nucleases and Transcription Activator-Like Effector Nucleases for Gene Targeting in Drosophila
por: Beumer, Kelly J., et al.
Publicado: (2013)

High frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
por: Fu, Yanfang, et al.
Publicado: (2013)

Broad Specificity Profiling of TALENs Results in Engineered Nucleases With Improved DNA Cleavage Specificity
por: Guilinger, John P., et al.
Publicado: (2014)

Zinc Finger Database (ZiFDB) v2.0: a comprehensive database of C(2)H(2) zinc fingers and engineered zinc finger arrays
por: Fu, Fengli, et al.
Publicado: (2013)

Evaluation of Methods to Assess in vivo Activity of Engineered Genome-Editing Nucleases in Protoplasts
por: Nadakuduti, Satya Swathi, et al.
Publicado: (2019)

Efficient In Vivo Genome Editing Using RNA-Guided Nucleases
por: Hwang, Woong Y., et al.
Publicado: (2013)

Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs)
por: Moore, Finola E., et al.
Publicado: (2012)

Hidden prevalence of deletion-inversion bi-alleles in CRISPR-mediated deletions of tandemly arrayed genes in plants
por: Liu, Jiuer, et al.
Publicado: (2023)

Revealing Off-Target Cleavage Specificities of Zinc Finger Nucleases by In Vitro Selection
por: Pattanayak, Vikram, et al.
Publicado: (2011)

Using defined finger–finger interfaces as units of assembly for constructing zinc-finger nucleases
por: Zhu, Cong, et al.
Publicado: (2013)

Geminivirus-Mediated Genome Editing in Potato (Solanum tuberosum L.) Using Sequence-Specific Nucleases
por: Butler, Nathaniel M., et al.
Publicado: (2016)

Targeted genome engineering via zinc finger nucleases
por: Kim, Seokjoong, et al.
Publicado: (2010)

Zinc Finger Nucleases as tools to understand and treat human diseases
por: Davis, David, et al.
Publicado: (2010)

Highly active zinc-finger nucleases by extended modular assembly
por: Bhakta, Mital S., et al.
Publicado: (2013)

Zinc Finger Nucleases: A new era for transgenic animals
por: Swarthout, John T., et al.
Publicado: (2011)

Simultaneous Screening and Validation of Effective Zinc Finger Nucleases in Yeast
por: Wang, Ling, et al.
Publicado: (2013)

Genome editing in plants via designed zinc finger nucleases
por: Petolino, Joseph F.
Publicado: (2015)

Evaluating the effect of chromosomal context on zinc finger nuclease efficiency
por: Bahr, Scott, et al.
Publicado: (2013)

Knockout of Myostatin by Zinc-finger Nuclease in Sheep Fibroblasts and Embryos
por: Zhang, Xuemei, et al.
Publicado: (2016)

Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases
por: Gupta, Ankit, et al.
Publicado: (2011)

Design and Development of Artificial Zinc Finger Transcription Factors and Zinc Finger Nucleases to the hTERT Locus
por: Wilson, Kimberly A, et al.
Publicado: (2013)

Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats
por: Liška, František, et al.
Publicado: (2016)

Correction: Targeting of the Plzf Gene in the Rat by Transcription Activator-Like Effector Nuclease Results in Caudal Regression Syndrome in Spontaneously Hypertensive Rats
por: Liška, František, et al.
Publicado: (2020)

Donor DNA Utilization During Gene Targeting with Zinc-Finger Nucleases
por: Beumer, Kelly J., et al.
Publicado: (2013)

Cancer translocations in human cells induced by zinc finger and TALE nucleases
por: Piganeau, Marion, et al.
Publicado: (2013)

Gene Targeting in NOD Mouse Embryos Using Zinc-Finger Nucleases
por: Chen, Yi-Guang, et al.
Publicado: (2014)

Efficient targeted mutagenesis in the monarch butterfly using zinc-finger nucleases
por: Merlin, Christine, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_403eq25g4kkdker2j46ebjn2ms