Comparing Zinc Finger Nucleases and Transcription Activator-Like Effector Nucleases for Gene Targeting in Drosophila

Zinc-finger nucleases have proven to be successful as reagents for targeted genome manipulation in Drosophila melanogaster and many other organisms. Their utility has been limited, however, by the significant failure rate of new designs, reflecting the complexity of DNA recognition by zinc fingers....

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Detalles Bibliográficos
Autores principales: Beumer, Kelly J., Trautman, Jonathan K., Christian, Michelle, Dahlem, Timothy J., Lake, Cathleen M., Hawley, R. Scott, Grunwald, David J., Voytas, Daniel F., Carroll, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789796/
https://www.ncbi.nlm.nih.gov/pubmed/23979928
http://dx.doi.org/10.1534/g3.113.007260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789796/
https://www.ncbi.nlm.nih.gov/pubmed/23979928
http://dx.doi.org/10.1534/g3.113.007260

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