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Global Linkage Map Connects Meiotic Centromere Function to Chromosome Size in Budding Yeast

Synthetic genetic array (SGA) analysis automates yeast genetics, enabling high-throughput construction of ordered arrays of double mutants. Quantitative colony sizes derived from SGA analysis can be used to measure cellular fitness and score for genetic interactions, such as synthetic lethality. Her...

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Detalles Bibliográficos
Autores principales: Baryshnikova, Anastasia, VanderSluis, Benjamin, Costanzo, Michael, Myers, Chad L., Cha, Rita S., Andrews, Brenda, Boone, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789798/
https://www.ncbi.nlm.nih.gov/pubmed/23979930
http://dx.doi.org/10.1534/g3.113.007377