APOBEC3G Polymorphism as a Selective Barrier to Cross-Species Transmission and Emergence of Pathogenic SIV and AIDS in a Primate Host

Cellular restriction factors, which render cells intrinsically resistant to viruses, potentially impose genetic barriers to cross-species transmission and emergence of viral pathogens in nature. One such factor is APOBEC3G. To overcome APOBEC3G-mediated restriction, many lentiviruses encode Vif, a p...

Descripción completa

Detalles Bibliográficos
Autores principales: Krupp, Annabel, McCarthy, Kevin R., Ooms, Marcel, Letko, Michael, Morgan, Jennifer S., Simon, Viviana, Johnson, Welkin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789815/
https://www.ncbi.nlm.nih.gov/pubmed/24098115
http://dx.doi.org/10.1371/journal.ppat.1003641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789815/
https://www.ncbi.nlm.nih.gov/pubmed/24098115
http://dx.doi.org/10.1371/journal.ppat.1003641

Ejemplares similares