A GDF5 Point Mutation Strikes Twice - Causing BDA1 and SYNS2

Growth and Differentiation Factor 5 (GDF5) is a secreted growth factor that belongs to the Bone Morphogenetic Protein (BMP) family and plays a pivotal role during limb development. GDF5 is a susceptibility gene for osteoarthritis (OA) and mutations in GDF5 are associated with a wide variety of skele...

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Detalles Bibliográficos
Autores principales: Degenkolbe, Elisa, König, Jana, Zimmer, Julia, Walther, Maria, Reißner, Carsten, Nickel, Joachim, Plöger, Frank, Raspopovic, Jelena, Sharpe, James, Dathe, Katarina, Hecht, Jacqueline T., Mundlos, Stefan, Doelken, Sandra C., Seemann, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789827/
https://www.ncbi.nlm.nih.gov/pubmed/24098149
http://dx.doi.org/10.1371/journal.pgen.1003846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789827/
https://www.ncbi.nlm.nih.gov/pubmed/24098149
http://dx.doi.org/10.1371/journal.pgen.1003846

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