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Genetic Architecture of Skewed X Inactivation in the Laboratory Mouse

X chromosome inactivation (XCI) is the mammalian mechanism of dosage compensation that balances X-linked gene expression between the sexes. Early during female development, each cell of the embryo proper independently inactivates one of its two parental X-chromosomes. In mice, the choice of which X...

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Detalles Bibliográficos
Autores principales: Calaway, John D., Lenarcic, Alan B., Didion, John P., Wang, Jeremy R., Searle, Jeremy B., McMillan, Leonard, Valdar, William, Pardo-Manuel de Villena, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789830/
https://www.ncbi.nlm.nih.gov/pubmed/24098153
http://dx.doi.org/10.1371/journal.pgen.1003853