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Genetic Architecture of Skewed X Inactivation in the Laboratory Mouse
X chromosome inactivation (XCI) is the mammalian mechanism of dosage compensation that balances X-linked gene expression between the sexes. Early during female development, each cell of the embryo proper independently inactivates one of its two parental X-chromosomes. In mice, the choice of which X...
Autores principales: | Calaway, John D., Lenarcic, Alan B., Didion, John P., Wang, Jeremy R., Searle, Jeremy B., McMillan, Leonard, Valdar, William, Pardo-Manuel de Villena, Fernando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789830/ https://www.ncbi.nlm.nih.gov/pubmed/24098153 http://dx.doi.org/10.1371/journal.pgen.1003853 |
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