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Transfer of human α-synuclein from the olfactory bulb to interconnected brain regions in mice

α-Synuclein (α-syn) is a protein prevalent in neural tissue and known to undergo axonal transport. Intracellular α-syn aggregates are a hallmark of Parkinson’s disease (PD). Braak and collaborators have suggested that in people who are destined to eventually develop PD, α-syn aggregate pathology pro...

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Detalles Bibliográficos
Autores principales: Rey, Nolwen L., Petit, Geraldine H., Bousset, Luc, Melki, Ronald, Brundin, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789892/
https://www.ncbi.nlm.nih.gov/pubmed/23925565
http://dx.doi.org/10.1007/s00401-013-1160-3