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Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis
BACKGROUND: The expression of SMAD4, the central component of the transforming growth factor-β (TGF-β) and bone morphogenetic protein (BMP) signalling pathways, is lost in 50% of pancreatic cancers and is associated with a poor survival. Although the TGF-β pathway has been extensively studied and ch...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790157/ https://www.ncbi.nlm.nih.gov/pubmed/23969729 http://dx.doi.org/10.1038/bjc.2013.486 |