Higher capecitabine AUC in elderly patients with advanced colorectal cancer (SWOGS0030)

BACKGROUND: The aging process is accompanied by physiological changes including reduced glomerular filtration and hepatic function, as well as changes in gastric secretions. To investigate what effect would aging have on the disposition of capecitabine and its metabolites, the pharmacokinetics betwe...

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Detalles Bibliográficos
Autores principales: Louie, S G, Ely, B, Lenz, H-J, Albain, K S, Gotay, C, Coleman, D, Raghavan, D, Shields, A F, Gold, P J, Blanke, C D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790171/
https://www.ncbi.nlm.nih.gov/pubmed/24022189
http://dx.doi.org/10.1038/bjc.2013.517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790171/
https://www.ncbi.nlm.nih.gov/pubmed/24022189
http://dx.doi.org/10.1038/bjc.2013.517

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