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Higher capecitabine AUC in elderly patients with advanced colorectal cancer (SWOGS0030)
BACKGROUND: The aging process is accompanied by physiological changes including reduced glomerular filtration and hepatic function, as well as changes in gastric secretions. To investigate what effect would aging have on the disposition of capecitabine and its metabolites, the pharmacokinetics betwe...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790171/ https://www.ncbi.nlm.nih.gov/pubmed/24022189 http://dx.doi.org/10.1038/bjc.2013.517 |