Targeting EGFR and PI3K pathways in ovarian cancer

BACKGROUND: The epidermal growth factor receptor (EGFR) is expressed in ovarian cancer, but agents targeting this pathway have shown little effect as single agents. This may be due to the presence of alternative pathways, particularly activation of the PI3K/Akt/MTOR pathway. METHODS: We have therefo...

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Detalles Bibliográficos
Autores principales: Glaysher, S, Bolton, L M, Johnson, P, Atkey, N, Dyson, M, Torrance, C, Cree, I A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790180/
https://www.ncbi.nlm.nih.gov/pubmed/24022196
http://dx.doi.org/10.1038/bjc.2013.529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790180/
https://www.ncbi.nlm.nih.gov/pubmed/24022196
http://dx.doi.org/10.1038/bjc.2013.529

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