PIAS4 is an activator of hypoxia signalling via VHL suppression during growth of pancreatic cancer cells

BACKGROUND: The PIAS4 protein belongs to the family of protein inhibitors of activated STAT, but has since been implicated in various biological activities including the post-translational modification known as sumoylation. In this study, we explored the roles of PIAS4 in pancreatic tumourigenesis....

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Detalles Bibliográficos
Autores principales: Chien, W, Lee, K L, Ding, L W, Wuensche, P, Kato, H, Doan, N B, Poellinger, L, Said, J W, Koeffler, H P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790182/
https://www.ncbi.nlm.nih.gov/pubmed/24002598
http://dx.doi.org/10.1038/bjc.2013.531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790182/
https://www.ncbi.nlm.nih.gov/pubmed/24002598
http://dx.doi.org/10.1038/bjc.2013.531

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