Personalized prediction of EGFR mutation-induced drug resistance in lung cancer

EGFR mutation-induced drug resistance has significantly impaired the potency of small molecule tyrosine kinase inhibitors in lung cancer treatment. Computational approaches can provide powerful and efficient techniques in the investigation of drug resistance. In our work, the EGFR mutation feature i...

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Detalles Bibliográficos
Autores principales: Wang, Debby D., Zhou, Weiqiang, Yan, Hong, Wong, Maria, Lee, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790204/
https://www.ncbi.nlm.nih.gov/pubmed/24092472
http://dx.doi.org/10.1038/srep02855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790204/
https://www.ncbi.nlm.nih.gov/pubmed/24092472
http://dx.doi.org/10.1038/srep02855

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