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Perturbations to the Ubiquitin Conjugate Proteome in Yeast Δubx Mutants Identify Ubx2 as a Regulator of Membrane Lipid Composition

Yeast Cdc48 (p97/VCP in human cells) is a hexameric AAA ATPase that is thought to use ATP hydrolysis to power the segregation of ubiquitin-conjugated proteins from tightly bound partners. Current models posit that Cdc48 is linked to its substrates through adaptor proteins, including a family of seve...

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Detalles Bibliográficos
Autores principales: Kolawa, Natalie, Sweredoski, Michael J., Graham, Robert L.J., Oania, Robert, Hess, Sonja, Deshaies, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790291/
https://www.ncbi.nlm.nih.gov/pubmed/23793018
http://dx.doi.org/10.1074/mcp.M113.030163