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tert-Butyl 4-{[2-amino-4-(2-hy­droxy­phen­yl)pyrimidin-5-yl]meth­yl}piperazine-1-carboxyl­ate

In the title compound, C(20)H(27)N(5)O(3), the central piperazine ring adopts a chair conformation, with the N-bound carboxyl­ate and methyl­ene substituents occupying bis­ectional and equatorial orientations, respectively. A twist is evident between the aromatic rings [dihedral angle = 25.61 (9)°]...

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Detalles Bibliográficos
Autores principales: Gajera, Nilesh N., Patel, Mukesh C., Jotani, Mukesh M., Tiekink, Edward R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790435/
https://www.ncbi.nlm.nih.gov/pubmed/24098254
http://dx.doi.org/10.1107/S1600536813025774