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Human SNP Links Differential Outcomes in Inflammatory and Infectious Disease to a FOXO3-Regulated Pathway

The clinical course and eventual outcome, or prognosis, of complex diseases varies enormously between affected individuals. This variability critically determines the impact a disease has on a patient’s life but is very poorly understood. Here, we exploit existing genome-wide association study data...

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Detalles Bibliográficos
Autores principales: Lee, James C., Espéli, Marion, Anderson, Carl A., Linterman, Michelle A., Pocock, Joanna M., Williams, Naomi J., Roberts, Rebecca, Viatte, Sebastien, Fu, Bo, Peshu, Norbert, Hien, Tran Tinh, Phu, Nguyen Hoan, Wesley, Emma, Edwards, Cathryn, Ahmad, Tariq, Mansfield, John C., Gearry, Richard, Dunstan, Sarah, Williams, Thomas N., Barton, Anne, Vinuesa, Carola G., Parkes, Miles, Lyons, Paul A., Smith, Kenneth G.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790457/
https://www.ncbi.nlm.nih.gov/pubmed/24035192
http://dx.doi.org/10.1016/j.cell.2013.08.034