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The impact of specific and non-specific immunity on the ecology of Streptococcus pneumoniae and the implications for vaccination

More than 90 capsular serotypes of Streptococcus pneumoniae coexist despite competing for nasopharyngeal carriage and a gradient in fitness. The underlying mechanisms for this are poorly understood and make assessment of the likely population impact of vaccination challenging. We use an individual-b...

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Detalles Bibliográficos
Autores principales: Flasche, Stefan, Edmunds, W. John, Miller, Elizabeth, Goldblatt, David, Robertson, Chris, Choi, Yoon Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790488/
https://www.ncbi.nlm.nih.gov/pubmed/24089337
http://dx.doi.org/10.1098/rspb.2013.1939