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Understanding the Impact of 2D and 3D Fibroblast Cultures on In Vitro Breast Cancer Models

The utilization of 3D, physiologically relevant in vitro cancer models to investigate complex interactions between tumor and stroma has been increasing. Prior work has generally focused on the cancer cells and, the role of fibroblast culture conditions on tumor-stromal cell interactions is still lar...

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Detalles Bibliográficos
Autores principales: Sung, Kyung Eun, Su, Xiaojing, Berthier, Erwin, Pehlke, Carolyn, Friedl, Andreas, Beebe, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790689/
https://www.ncbi.nlm.nih.gov/pubmed/24124550
http://dx.doi.org/10.1371/journal.pone.0076373