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Screening E3 Substrates Using a Live Phage Display Library

Ubiquitin ligases (E3s) determine specificity of ubiquitination by recognizing target substrates. However, most of their substrates are unknown. Most known substrates have been identified using distinct approaches in different laboratories. We developed a high-throughput strategy using a live phage...

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Detalles Bibliográficos
Autores principales: Guo, Zhengguang, Wang, Xiaorong, Li, Huihua, Gao, Youhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790729/
https://www.ncbi.nlm.nih.gov/pubmed/24124579
http://dx.doi.org/10.1371/journal.pone.0076622