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Screening E3 Substrates Using a Live Phage Display Library
Ubiquitin ligases (E3s) determine specificity of ubiquitination by recognizing target substrates. However, most of their substrates are unknown. Most known substrates have been identified using distinct approaches in different laboratories. We developed a high-throughput strategy using a live phage...
Autores principales: | Guo, Zhengguang, Wang, Xiaorong, Li, Huihua, Gao, Youhe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790729/ https://www.ncbi.nlm.nih.gov/pubmed/24124579 http://dx.doi.org/10.1371/journal.pone.0076622 |
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