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Role of an Indole-Thiazolidine Molecule PPAR Pan-Agonist and COX Inhibitor on Inflammation and Microcirculatory Damage in Acute Gastric Lesions

The present study aimed to show the in vivo mechanisms of action of an indole-thiazolidine molecule peroxisome-proliferator activated receptor pan-agonist (PPAR pan) and cyclooxygenase (COX) inhibitor, LYSO-7, in an ethanol/HCl-induced (Et/HCl) gastric lesion model. Swiss male mice were treated with...

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Detalles Bibliográficos
Autores principales: Santin, José Roberto, Daufenback Machado, Isabel, Rodrigues, Stephen F. P., Teixeira, Simone, Muscará, Marcelo N., Lins Galdino, Suely, da Rocha Pitta, Ivan, Farsky, Sandra H. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790743/
https://www.ncbi.nlm.nih.gov/pubmed/24124600
http://dx.doi.org/10.1371/journal.pone.0076894