Improving Acetate Tolerance of Escherichia coli by Rewiring Its Global Regulator cAMP Receptor Protein (CRP)

The presence of acetate exceeding 5 g/L is a major concern during E. coli fermentation due to its inhibitory effect on cell growth, thereby limiting high-density cell culture and recombinant protein production. Hence, engineered E. coli strains with enhanced acetate tolerance would be valuable for t...

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Detalles Bibliográficos
Autores principales: Chong, Huiqing, Yeow, Jianwei, Wang, Ivy, Song, Hao, Jiang, Rongrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790751/
https://www.ncbi.nlm.nih.gov/pubmed/24124618
http://dx.doi.org/10.1371/journal.pone.0077422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790751/
https://www.ncbi.nlm.nih.gov/pubmed/24124618
http://dx.doi.org/10.1371/journal.pone.0077422

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