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Impact of the Phosphatidylinositide 3-Kinase Signaling Pathway on the Cardioprotection Induced by Intermittent Hypoxia

BACKGROUND: Exposure to intermittent hypoxia (IH) may enhance cardiac function and protects heart against ischemia-reperfusion (I/R) injury. To elucidate the underlying mechanisms, we developed a cardioprotective IH model that was characterized at hemodynamic, biochemical and molecular levels. METHO...

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Detalles Bibliográficos
Autores principales: Milano, Giuseppina, Abruzzo, Provvidenza Maria, Bolotta, Alessandra, Marini, Marina, Terraneo, Laura, Ravara, Barbara, Gorza, Luisa, Vitadello, Maurizio, Burattini, Sabrina, Curzi, Davide, Falcieri, Elisabetta, von Segesser, Ludwig K., Samaja, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790757/
https://www.ncbi.nlm.nih.gov/pubmed/24124584
http://dx.doi.org/10.1371/journal.pone.0076659