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NF-κB Is Activated in CD4(+) iNKT Cells by Sickle Cell Disease and Mediates Rapid Induction of Adenosine A(2A) Receptors

Reperfusion injury following tissue ischemia occurs as a consequence of vaso-occlusion that is initiated by activation of invariant natural killer T (iNKT) cells. Sickle cell disease (SDC) results in widely disseminated microvascular ischemia and reperfusion injury as a result of vaso-occlusion by r...

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Detalles Bibliográficos
Autores principales: Lin, Gene, Field, Joshua J., Yu, Jennifer C., Ken, Ruey, Neuberg, Donna, Nathan, David G., Linden, Joel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790763/
https://www.ncbi.nlm.nih.gov/pubmed/24124453
http://dx.doi.org/10.1371/journal.pone.0074664