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Discovery of a New Genetic Variant of Methionine Aminopeptidase from Streptococci with Possible Post-Translational Modifications: Biochemical and Structural Characterization

Protein N-terminal methionine excision is an essential co-translational process that occurs in the cytoplasm of all organisms. About 60-70% of the newly synthesized proteins undergo this modification. Enzyme responsible for the removal of initiator methionine is methionine aminopeptidase (MetAP), wh...

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Detalles Bibliográficos
Autores principales: Arya, Tarun, Kishor, Chandan, Saddanapu, Venkateshwarlu, Reddi, Ravikumar, Addlagatta, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790777/
https://www.ncbi.nlm.nih.gov/pubmed/24124477
http://dx.doi.org/10.1371/journal.pone.0075207