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Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

Circulating lymphocytes continuously enter lymph nodes (LNs) for immune surveillance through specialised blood vessels named high endothelial venules (HEVs)(1–5), a process that increases dramatically during immune responses. How HEVs permit lymphocyte transmigration while maintaining vascular integ...

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Detalles Bibliográficos
Autores principales: Herzog, Brett H., Fu, Jianxin, Wilson, Stephen J., Hess, Paul R., Sen, Aslihan, McDaniel, J. Michael, Pan, Yanfang, Sheng, Minjia, Yago, Tadayuki, Silasi-Mansat, Robert, McGee, Samuel, May, Frauke, Nieswandt, Bernhard, Morris, Andrew J., Lupu, Florea, Coughlin, Shaun R., McEver, Rodger P., Chen, Hong, Kahn, Mark L., Xia, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791160/
https://www.ncbi.nlm.nih.gov/pubmed/23995678
http://dx.doi.org/10.1038/nature12501