Cargando…

A TLR6 polymorphism is associated with increased risk of Legionnaires’ Disease

Legionella pneumophila (Lp), the etiologic agent of Legionnaires’ Disease (LD), is an important cause of community-acquired and nosocomial pneumonia. However, the host immune and genetic determinants of human susceptibility to Lp are poorly understood. Here we show that both TLR6 and TLR1 cooperate...

Descripción completa

Detalles Bibliográficos
Autores principales: Misch, Elizabeth Ann, Verbon, Annelies, Prins, Jan M., Skerrett, Shawn J., Hawn, Thomas Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791179/
https://www.ncbi.nlm.nih.gov/pubmed/23823019
http://dx.doi.org/10.1038/gene.2013.34