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A TLR6 polymorphism is associated with increased risk of Legionnaires’ Disease
Legionella pneumophila (Lp), the etiologic agent of Legionnaires’ Disease (LD), is an important cause of community-acquired and nosocomial pneumonia. However, the host immune and genetic determinants of human susceptibility to Lp are poorly understood. Here we show that both TLR6 and TLR1 cooperate...
Autores principales: | Misch, Elizabeth Ann, Verbon, Annelies, Prins, Jan M., Skerrett, Shawn J., Hawn, Thomas Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791179/ https://www.ncbi.nlm.nih.gov/pubmed/23823019 http://dx.doi.org/10.1038/gene.2013.34 |
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