Contribution of PGE(2) EP1 receptor in hemin-induced neurotoxicity

Although hemin-mediated neurotoxicity has been linked to the production of free radicals and glutamate excitotoxicity, the role of the prostaglandin E(2) (PGE(2))-EP1 receptor remains unclear. Activation of the EP1 receptor in neurons results in increased intracellular calcium levels; therefore, we...

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Detalles Bibliográficos
Autores principales: Mohan, Shekher, Glushakov, Alexander V., deCurnou, Alexander, Narumiya, Shuh, Doré, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791386/
https://www.ncbi.nlm.nih.gov/pubmed/24109429
http://dx.doi.org/10.3389/fnmol.2013.00031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791386/
https://www.ncbi.nlm.nih.gov/pubmed/24109429
http://dx.doi.org/10.3389/fnmol.2013.00031

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