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Contribution of PGE(2) EP1 receptor in hemin-induced neurotoxicity
Although hemin-mediated neurotoxicity has been linked to the production of free radicals and glutamate excitotoxicity, the role of the prostaglandin E(2) (PGE(2))-EP1 receptor remains unclear. Activation of the EP1 receptor in neurons results in increased intracellular calcium levels; therefore, we...
Autores principales: | Mohan, Shekher, Glushakov, Alexander V., deCurnou, Alexander, Narumiya, Shuh, Doré, Sylvain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791386/ https://www.ncbi.nlm.nih.gov/pubmed/24109429 http://dx.doi.org/10.3389/fnmol.2013.00031 |
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