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Phytoestrogen Genistein Up-Regulates Endothelial Nitric Oxide Synthase Expression Via Activation of cAMP Response Element-Binding Protein in Human Aortic Endothelial Cells

We previously reported that genistein, a phytoestrogen, up-regulates endothelial nitric oxide synthase (eNOS) and prevents hypertension in rats that are independent of estrogen signaling machinery. However, how genistein regulates eNOS expression is unknown. In the present study, we show that genist...

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Detalles Bibliográficos
Autores principales: Si, Hongwei, Yu, Jie, Jiang, Hongling, Lum, Hazel, Liu, Dongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791435/
https://www.ncbi.nlm.nih.gov/pubmed/22669896
http://dx.doi.org/10.1210/en.2012-1076