Cargando…

Role of the C-terminal domain in the structure and function of tetrameric sodium channels

Voltage-gated sodium channels have essential roles in electrical signalling. Prokaryotic sodium channels are tetramers consisting of transmembrane (TM) voltage-sensing and pore domains, and a cytoplasmic carboxy-terminal domain. Previous crystal structures of bacterial sodium channels revealed the n...

Descripción completa

Detalles Bibliográficos
Autores principales: Bagnéris, Claire, DeCaen, Paul G., Hall, Benjamin A., Naylor, Claire E., Clapham, David E., Kay, Christopher W. M., Wallace, B. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791462/
https://www.ncbi.nlm.nih.gov/pubmed/24051986
http://dx.doi.org/10.1038/ncomms3465