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Structure of a helicase–helicase loader complex reveals insights into the mechanism of bacterial primosome assembly

During the assembly of the bacterial loader-dependent primosome, helicase loader proteins bind to the hexameric helicase ring, deliver it onto the oriC DNA and then dissociate from the complex. Here, to provide a better understanding of this key process, we report the crystal structure of the ~570-k...

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Detalles Bibliográficos
Autores principales: Liu, Bin, Eliason, William K., Steitz, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791466/
https://www.ncbi.nlm.nih.gov/pubmed/24048025
http://dx.doi.org/10.1038/ncomms3495